How Declining Health Begins - Microvascular

How Declining Health Begins

You may look—and even feel—healthy on the outside, but inside your microvascular system, a completely different situation could be developing.

Organ starvation is one reason that declining health and diseases begin in the body. When the capillaries begin to lose their function, vital organs don’t receive the nutrients needed to be healthy… the silent spiral of health decline begins.


Caused by High Blood Glucose Level
A healthy microvascular system is important for transport of glucose from blood to organs.
High blood glucose damages (micro) vascular system and causes blindness, kidney failure, heart attack and stroke.
High glucose from diabetes can result in capillaries being attacked, resulting in capillaries unable to deliver nutrients like glucose, hormones like insulin, and remove waste from cells. Endocalyx restores and maintains the endothelial glycocalyx lining inside the capillaries and improves capillary density and function*. Endocalyx also helps protect against damage from high glucose and oxidative stress*.
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Heart Disease

Loss of Pump Function of Heart
Loss of microvascular density causes heart attack
Insufficient number of capillaries per heart muscle fiber impairs heart pump function (heart failure).
Heart attack happens when a blood clot shuts down blood flow in a large artery. When the blood clot is removed blood flow is restored, but damage occurs in the microvessels due to formation of oxygen radicals. Endocalyx supports the health of the microvessels and limits reperfusion injury.*
Even in the absence of a large vessel blockage, people can experience chest pain (angina) due to inadequate microvascular blood flow and loss of capillaries. Endocalyx restores the glycocalyx lining inside the microvascular system and increases capillary density*.
Many people experience loss of cardiac function and suffer from a type of heart failure that is linked to loss of capillaries and increased stiffness of the heart muscle. Endocalyx restores the glycocalyx lining inside the microvessels and increases microvascular blood flow and capillary density that will contribute to improved heart function*.
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Blood Clot in Brain Artery Causing Brain Damage
Damage to vascular wall causes blood clots.
Microvascular damage causes White Matter Lesions with poor neurological prognosis.
Stroke occurs when a blood clot in a large artery blocks supply of oxygen and nutrients, resulting in brain damage. After removal or dissolving the clot and blood flow is restored to the brain, further damage occurs due to loss of capillaries by high levels of oxygen radicals. Endocalyx can protect the capillaries against this second challenge of high oxygen radicals by restoring the health of the glycocalyx lining*.
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Septic Shock

Loss of Circulation Blood Volume Causes Drop in Blood Pressure
Can lead to Impaired organ blood flow resulting in acute kidney failure, reduced lung function, heart attack, stroke and brain damage
Leaky microvessels result in loss of blood plasma volume to tissue space.
Damaged vascular wall causes increased blood clotting and inflammation.


Blood Pressure is Higher than Accepted Level
Hypertension is associated with loss of microvascular density.
Hypertension increases cardiovascular risk (heart attack, stroke, kidney failure).
Hypertension increases risk of stroke and cardiovascular disease and is associated with capillary loss. Endocalyx restores, regenerates, and protects the glycocalyx lining inside the capillaries so loss can be prevented, and organs including the brain, heart, and kidneys can be better protected*.
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Kidney Disease

Impaired Production of Urine Causing Increased Blood Volume and Hypertension
Damage of microvessels causes leakage of blood proteins into urinary space, damage of renal filtration units and kidney failure.
Breakdown of kidney capillaries causes loss of its filtering system and impairs production of urine, increasing blood volume and resulting in hypertension. Endocalyx restores the glycocalyx lining inside the capillaries so that kidney function can be optimized and preserved*.
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Early Cognition Impairment: Neurological Complication
Healthy microvascular system is essential to maintain intact neuro-vascular unit and support normal neurological function.
Dementia is associated with damage and the loss of capillary density in the brain. When capillaries are damaged, essential nutrients can’t nourish and oxygenate cells in the brain, and just as importantly, waste and carbon dioxide can’t be removed. Endocalyx restores the glycocalyx lining inside the capillaries so that capillary density can increase, with nutrients delivered to, and waste removed from cells in the brain*.
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Inflammatory Disorders

Rheumatoid Arthritis, Vasculitis, Allergies, Glomerulonephritis, Autoimmune Diseases, Scleroderma, and Atherosclerosis
Attack of microvascular system by inflammatory cells results in loss of capillaries.
Increased capillary permeability causes tissue edema.
Out-of-control activation of the inflammatory system in response to challenges like rheumatoid arthritis, vasculitis, allergies, glomerulonephritis, autoimmune diseases, scleroderma, and atherosclerosis. An attack on capillaries by inflammatory cells results in damage and loss of capillaries. Increased capillary permeability causes tissue edema. Endocalyx can restore the endothelial glycocalyx lining inside the capillaries, even after damage and the loss of capillary density*.
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Cancer Metastasis

Uncontrolled Growth of Tumors
Leaky microvessels allow tumor cells to enter the vascular system and redistribute to different parts of our body, causing tumor metastasis (secondary tumors).
A leaky microvascular system enables cancer cells to redistribute to different parts of the body. Endocalyx restores the glycocalyx lining of the microvessels to better contain the primary tumor and reduce metastasis*.
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