Endocalyx Pro Regenerates Your Microcirculation System

Endocalyx Pro™ is the only proprietary, patented anti-aging supplement that has been clinically shown to maintain a healthy glycocalyx.*

The glycocalyx is the micro-thin gel layer that lines the inside of all blood vessels throughout the body and all organs.

Endocalyx Pro provides the anti-aging building blocks needed for a strong and vital glycocalyx, strengthening this micro-thin shield that protects the heart, arteries, microcirculation and veins.* It helps keep blood vessels slick, smooth and protected inside, from the largest arteries and veins to the tiniest capillaries.* This keeps blood flowing freely while optimizing circulation throughout the entire body.* GlycoCheck testing is not required to take Endocalyx Pro.

  • Endocalyx Pro strengthens the glycocalyx and helps optimize the structure of the capillaries, which allows them to exchange oxygen and carbon dioxide, nutrients and waste more efficiently.*

  • Aging, diet, disease, lack of exercise, genetics, stress and smoking can cause the glycocalyx to become compromised.*

  • Endocalyx Pro promotes healthy organs associated with vascular health, including the heart, brain, kidneys, lung, muscle, skin and eyes.*

  • When the glycocalyx is thick and strong, it serves as a barrier to oxidants, fats and cholesterol.*

  • You can preventatively take Endocalyx Pro, even without being tested for your MicroVascular Health Score in a healthcare provider’s office.

Dr. David Haase

MaxWell Clinic

"It is microcirculation that is the business end of all lifestyle and nutritional interventions as that is where the nutrients are delivered and waste is removed from the BRAIN, KIDNEYS, PENIS, HEART, LUNGS, EYES, NERVES, MUSCLE … every organ. When you repair and protect the microcirculation, you protect yourself from premature health decline.”

Patented Formulation with Three Classes of Compounds

Restorative Properties of Polysaccharides: Endocalyx Pro is made with a brown seaweed called Laminaria Japonica. An extract is produced that is certified to have a minimum extract rate of 85% of the compound fucoidan sulfate. Fucoidan sulfate is validated as a hybrid of heparan sulfate and chondroitin sulfate and has a high binding affinity for heparanase. The fucoidan repairs the glycocalyx and prevents breakdown by inhibiting the heparanase activity. In addition to the fucoidan sulfate, Endocalyx Pro also contains high molecular weight hyaluronan which is essential to provide the glycocalyx with its structural stability and dimension.

Regenerative Properties of Amino Sugars: A high dose of glucosamine sulfate, 1,500 mg (vegetarian) provides the building blocks for glycocalyx synthesis. Research confirms that glucosamine at this concentration boosts endothelial cell glycocalyx production.

Protective Properties of Antioxidants: Microvascular Health Solutions developed a next-generation proprietary blend of polyphenol and flavonoids consisting of the most efficacious fruits and vegetables clinically shown to produce anti-oxidant activity. Olive (fruit) extract, artichoke (leaf) extract, red and white grapes (fruit) extract. We increased the amounts of these ingredients to provide evidence based effective doses. We added superoxide dismutase (from bitter melon concentrate). We also added catalase (also from bitter melon concentrate). It is also verified that these antioxidant ingredients survive oral intake and arrive in the vascular compartment at clinically effective dosages.

Recommended dose: Four capsules twice daily, either two in the morning and two in the evening, or four all at one time. One bottle of 120 veggie capsules is a one-month supply.

Patents: Filed and Granted as a Method of Treatment for the Endothelial Glycocalyx based on the synergistic action of three classes of compounds. This patented anti-aging supplement formula has been clinically shown to improve the health of the glycocalyx using seven synergistic ingredients from three classes of compounds:

RESTORE: Polysaccharides – enables repair of glycocalyx matrix (fucoidan sulfate and HMW hylaronan)

REGENERATE: Amino sugars – precursor for polysaccharide biosynthesis (veggie glucosamine)

PROTECT: Antioxidants – protects endothelial polysaccharide from breakdown (polyphenol, flavonoids, SOD, heparanase inhibitor).


United States: 9943572
Europe: EP3280423
China: ZL 201680033444.2
Japan: 6518796
South Korea: 10-1972691
Canada (Pending): 3020277
World Intellectual Property Organization