Endocalyx Pro Studies

Cardiovascular Disease

Study	Research Group	Where Published
Adaptations of Arterial Function and Endothelial Glycocalyx to High-Sodium Diet in Mice	Florida State University	FSU Digital Repository
Effect of Glycocalyx-targeted Therapy on Vascular Function in Older Adults: A Randomized Controlled Trial	University of Iowa	Journal of Applied Physiology

Aging

Study	Research Group	Where Published
Sex differences in endothelial glycocalyx thickness and the response to glycocalyx‐targeted therapy among older adults	University of Iowa	Physiological Report
Glycocalyx-targeted therapy ameliorates age-related arterial dysfunction	University of Utah; Florida State University	GeroScience

Arterial Stiffness/Cardiovascular Disease/Diabetes

Study	Research Group	Where Published
Diabetes Study Abstract: Glycocalyx Restoration Reduces Arterial Stiffness In Diabetic Female Mice	University of Utah; University of Missouri	Hypertension

Arterial Stiffness/Psoriatic Disease

Study	Research Group	Where Published
The effect of 4-month treatment with a dietary supplement containing glycosaminoglycans and fucoidanon endothelial glycocalyx integrity and vascular function in patients with psoriatic disease	Attikon University Hospital, National & Kapodistrian University of Athens, 12461 Athens, Greece	European Heart Journal Cardiovascular Imaging

Covid-19

Study	Research Group	Where Published
The effect of a dietary supplement containing glycosaminoglycans and fucoidanon endothelial glycocalyx integrity and vascular function in patients after COVID-19 infection	Attikon University Hospital, National & Kapodistrian University of Athens, 12461 Athens, Greece	European Heart Journal Cardiovascular Imaging
Effects of 4-month treatment with glycocalyx dietary supplement on endothelial glycocalyx and vascular function after COVID-19 infection	Attikon University Hospital, National & Kapodistrian University of Athens, 12461 Athens, Greece	European Journal of Clinical Investigation

Diabetes

Study	Research Group	Where Published
Supplementation with Endocalyx Pro preserves glomerular endothelial glycocalyx and capillary stability in experimental diabetes (Chapter 5 of Thesis)	Leiden University, The Neterlands	*Published as a dissertation (see Chapter 5); not yet on a publication site
Role of dietary interventions on microvascular health in South-Asian Surinamese people with type 2 diabetes in the Netherlands; a randomized controlled trial	Leiden University, The Neterlands; Haaglanden Medical Center, The Netherlands; Radbound University Medical Center	Nutrition and Diabetes

Diabetes (Diabetic Nephropathy)

Study	Research Group	Where Published
Role of dietary interventions on microvascular health in South-Asian Surinamese people with type 2 diabetes in the Netherlands: A randomized controlled trial	Leiden University, The Neterlands; Green Heart Hospital, The Netherlands; Haaglanden Medical Center, The Netherlands	Nutrition and Diabetes

Kidney Disease (Chronic Kidney Disease Damage)

Study	Research Group	Where Published
A Dietary Supplement Containing Fucoidan Preserves Endothelial Glycocalyx through ERK/MAPK Signaling and Protects against Damage Induced by CKD Serum	University Hospital Munster, Germany; Maasctricht University, The Netherlands	International Journal of Molecular Sciences

Kidney Disease (Regeneration)

Study	Research Group	Where Published
Ways and Means of Cellular Reconditioning for Kidney Regeneration	New York Medical College	American Journal of Nephrology

Psoriasis

Study	Research Group	Where Published
The Effect of 4-Month Treatment with Glycocalyx Dietary Supplement on Endothelial Glycocalyx Integrity and Vascular Function in Patients with Psoriasis	Attikon University Hospital, National & Kapodistrian University of Athens, 12461 Athens, Greece	Nutrients

Type 2 Diabetes

Study	Research Group	Where Published
Impact of dietary supplementation of glycocalyx precursors on vascular function in type 2 diabetes	University of Missouri	Journal of Applied Physiology

Vascular Aging

Study	Research Group	Where Published
Dietary Glycocalyx Precursor Supplementation Ameliorates Age-Related Vascular Dysfunction	University of Utah	Federation of American Societies for Experimental Biology

Ingredient Studies (Covid-19 (Patients in ICU))

Study	Research Group	Where Published
Heparan sulfate mimetic fucoidan restores the endothelial glycocalyx and protects against dysfunction induced by serum of COVID-19 patients in the intensive care unit	Beat COVID Study Group	European Respiratory Journal (ER\J)

Trials

Study	Research Group	Where Published
Hypertension - Glycocalyx restoration in treatment resistant hypertension	Amsterdam Medical Center	Clinical Trials
Diabetes (Vascular Function) - Targeting the Endothelial Glycocalyx to Enhance Vascular Function and Exercise-Induced Vascular Adaptations in Type 2 Diabetes	VA Office of Research and Development	Clinical Trials

Study Proposals

Study	Research Group	Where Published
Sepsis - Sepsis Study Summary: Endocalyx Pro™ in animal sepsis proposal.

Recommendation to Study Endocalyx and Arterosil

Study	Research Group	Where Published
Alzheimer's Disease and ischemic stroke - Focus of endothelial glycocalyx dysfunction in ischemic stroke and Alzheimer’s disease: Possible intervention strategies	University of Palermo, Italy;	ScienceDirect (a PDF has been paid for and downloaded). This paper cites Endocalyx as a possible nutraceutical for future testing
Cardiovascular Disease - Regeneration and Assessment of the Endothelial Glycocalyx To Address Cardiovascular Disease

Study Proposals Underway

Study
Arterial Plaque Development
Emergency Room Admissions
Erectile Dysfunction
Hair Growth
Scleroderma