Endocalyx™ is a proprietary, patented nutraceutical that has been clinically shown to maintain a healthy glycocalyx.*

The glycocalyx is the micro-thin gel layer that lines the inside of all blood vessels throughout the body and all organs.

Endocalyx provides the building blocks needed for a strong and vital glycocalyx, strengthening this micro-thin shield that protects the heart, arteries, microcirculation and veins.* It helps keep blood vessels slick, smooth and protected inside, from the largest arteries and veins to the tiniest capillaries.* This keeps blood flowing freely while optimizing circulation throughout the entire body.*

  • It strengthens the glycocalyx and helps optimize the structure of the capillaries, which allows them to exchange oxygen and carbon dioxide, nutrients and waste more efficiently.*
  • Aging, diet, disease, lack of exercise, genetics, stress and smoking can cause the glycocalyx to become compromised.*
  • Endocalyx promotes healthy organs associated with vascular health, including the heart, brain, kidneys, lung, muscle, skin and eyes.*
  • When the glycocalyx is thick and strong, it serves as a barrier to oxidants, fats and cholesterol.*
  • You can preventatively take Endocalyx, even without being tested for your MicroVascular Health Score in a healthcare provider’s office.

Three synergistic actions restore, regenerate and protect the microvascular circulation system.


This patented nutraceutical formula has been clinically shown to improve the health of the glycocalyx using seven synergistic ingredients from three classes of compounds:


RESTORE: Polysaccharides – enables repair of glycocalyx matrix


REGENERATE: Amino sugars – precursor for polysaccharide biosynthesis


PROTECT: Antioxidants – protects endothelial polysaccharide from breakdown

  • Polysaccharides are long sugar chains that can interact with proteins and other molecules of the glycocalyx to restore its protective structure.
  • Amino sugars enable the cells of the vessel wall to produce more glycocalyx polysaccharides and regenerate the body’s ability to produce more of the protective gel.
  • Antioxidants protect the polysaccharides of the glycocalyx from breaking down.


Unhealthy Microcirculation

(Month 0; before taking Endocalyx)
Low MicroVascular Health Score 0.6


Healthy Microcirculation

(Month 4 after taking Endocalyx)
High MicroVascular Health Score 3.9

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